STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ubiEMethyltransferase, ubiquinone biosynthesis; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (276 aa)    
Predicted Functional Partners:
ABO_2599
Oxygenase; Family membership.
  
 
 0.945
coq7
Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
   
 
 0.912
wrbA
Trp repressor binding protein; Identified by sequence similarity; putative InterPro: Flavodoxin; Family membership; Belongs to the WrbA family.
     
  0.900
ABO_2247
Conserved hypothetical protein.
  
  
 0.889
ABO_2248
Ubiquinone biosynthesis protein, putative; (conserved hypothetical protein) identified by Glimmer2; putative InterPro: ABC1 family; High confidence in function and specificity.
  
  
 0.818
hisE
phosphoribosyl-ATP pyrophosphatase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01503 InterPro: Phosphoribosyl-ATP pyrophosphohydrolase; High confidence in function and specificity.
  
   0.634
ubiA
UbiA prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
   
 0.598
ubiG
3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.586
ABO_0451
Transferases identified by sequence similarity; putative InterPro: Polyprenyl synthetase; Function unclear; Belongs to the FPP/GGPP synthase family.
 
 
 0.584
tatC
Sec-independent periplasmic protein translocator TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
 
   
 0.558
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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