Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ctpACarboxyl-terminal protease; Identified by match to PFAM protein family HMMPF03572 InterPro: Carboxyl-terminal protease; High confidence in function and specificity; Belongs to the peptidase S41A family. (433 aa)    
Predicted Functional Partners:
ABO_0521
TPR domain protein; Identified by match to PFAM protein family HMMPF00515; Specificity unclear.
 
 
 0.837
ABO_2275
Conserved hypothetical protein.
 
  
 0.811
ABO_2277
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.811
ABO_2041
Identified by match to PFAM protein family HMMPF00877 InterPro: NLP/P60; Function unclear.
    
 
 0.546
ABO_2274
(rhodanese domain protein, putative) identified by similarity to PFAMB protein family PB095705 PB094266 PB093724 PB092780 PB092388 PB091758 PB086012 PB074034 PB071888 PB045826 PB027182 PB012820 PB012628 PB009308 PB006481; putative InterPro: Rhodanese/cdc25 fold; Family membership.
  
    0.537
ABO_1150
Identified by match to PFAM protein family HMMPF02163 InterPro: Putative membrane-associated zinc metalloprotease; Function unclear.
 
  
 0.511
def-1
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
     0.469
secB
Protein-transport protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
       0.468
ABO_2273
Glutaredoxin, putative; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
     
 0.456
lepB
(signal peptidase I) identified by sequence similarity; InterPro: Signal peptidase; High confidence in function and specificity; Belongs to the peptidase S26 family.
 
  
 0.423
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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