| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABO_2283 | ABO_2284 | ABO_2283 | ABO_2284 | (sensor histidine kinase, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.558 |
| ABO_2283 | ABO_2286 | ABO_2283 | ABO_2286 | (sensor histidine kinase, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.400 |
| ABO_2283 | mutY | ABO_2283 | ABO_2285 | (sensor histidine kinase, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership. | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.454 |
| ABO_2284 | ABO_2283 | ABO_2284 | ABO_2283 | Conserved hypothetical protein; Identified by Glimmer2; putative. | (sensor histidine kinase, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership. | 0.558 |
| ABO_2284 | ABO_2286 | ABO_2284 | ABO_2286 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.662 |
| ABO_2284 | mutY | ABO_2284 | ABO_2285 | Conserved hypothetical protein; Identified by Glimmer2; putative. | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.731 |
| ABO_2286 | ABO_2283 | ABO_2286 | ABO_2283 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | (sensor histidine kinase, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership. | 0.400 |
| ABO_2286 | ABO_2284 | ABO_2286 | ABO_2284 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.662 |
| ABO_2286 | mutY | ABO_2286 | ABO_2285 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.802 |
| ABO_2580 | mutY | ABO_2580 | ABO_2285 | Coproporphyrinogen oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.436 |
| birA | mutY | ABO_0368 | ABO_2285 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.444 |
| birA | xthA | ABO_0368 | ABO_1485 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | (xth), (Exonuclease III),(EXO III),(APendonuclease VI). identified by sequencesimilarity; putative InterPro: AP endonucleases family 1 Exodeoxyribonuclease III xth; High confidence in function and specificity. | 0.788 |
| dnaN | mutL | ABO_0002 | ABO_2205 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.918 |
| dnaN | mutY | ABO_0002 | ABO_2285 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.510 |
| dnaN | polA | ABO_0002 | ABO_2659 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
| dnaN | xthA | ABO_0002 | ABO_1485 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | (xth), (Exonuclease III),(EXO III),(APendonuclease VI). identified by sequencesimilarity; putative InterPro: AP endonucleases family 1 Exodeoxyribonuclease III xth; High confidence in function and specificity. | 0.865 |
| mutL | dnaN | ABO_2205 | ABO_0002 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.918 |
| mutL | mutY | ABO_2205 | ABO_2285 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.449 |
| mutL | polA | ABO_2205 | ABO_2659 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.961 |
| mutY | ABO_2283 | ABO_2285 | ABO_2283 | A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | (sensor histidine kinase, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership. | 0.454 |