Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
waaF(ADP-heptose--LPS heptosyltransferase II, putative); identify by similarity to InterPro IPR002201 and PFAM protein family PF01075. InterPro IPR002201; Glyco_trans_9. lipopolysaccharide core biosynthesis; High confidence in function and specificity. (351 aa)    
Predicted Functional Partners:
waaC
(heptosyltransferase I); High confidence in function and specificity.
 
0.994
waaG
UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase; (rfag) (lipopolysaccharide core biosynthesis protein, glucosyltransferase family 1) identified by match to PFAM protein family HMMPF00534 InterPro: Glycosyl transferases group 1; High confidence in function and specificity.
 
 
 0.990
waaP2
Lipopolysaccharide core kinase; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.
 
 
 0.987
ABO_0007
Histidinol-phosphatase, putatitve; Identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00213; Function unclear.
   
 0.976
waaA
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.969
ABO_2215
Heptosyltransferase II, putatative; Heptosyltransferase II; identified by sequence similarity; putative InterPro: Glycosyltransferase family 9 Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core; High confidence in function and specificity.
 
 
0.963
rfaE
LPS biosynthesis protein RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
 
   
 0.876
waaP1
Lipopolysaacharide kinase; Identified by sequence similarity; Family membership.
  
 
 0.855
ABO_2294
Conserved hypothetical protein; Identify by sequence similarity KDO kinase-like domain.
   
 
 0.851
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.813
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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