Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_2350Conserved hypothetical protein. (217 aa)    
Predicted Functional Partners:
plsC1
1-acyl-sn-glycerol-3-phosphate acyltransferase; (plsC) identified by sequence similarity; putative InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); High confidence in function and specificity; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
      0.841
ABO_2351
(universal stress protein family) identified by match to PFAM protein family HMMPF00582.
       0.811
hisF
Imidazoleglycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.619
hisZ
ATP phosphoribosyl transferase regulatory subunit, putative; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
 
    0.597
nudH
(di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
       0.585
hisH
Glutamine amidotransferase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.551
ptsP
(phosphoenolpyruvate-protein phosphotransferasePtsP) identified by sequencesimilarity; putative InterPro: PEP-utilizing enzyme; High confidence in function and specificity; Belongs to the PEP-utilizing enzyme family.
       0.525
dapD
Tetrahydrodipicolinate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
  
  
 0.515
hisA
Phosphoribosylformimino-5-aminoimidazolecarboxam ide ribotide; (1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)met hylideneamino] imidazole-4-carboxamide isomerase, phosphoribosylformimino-5-aminoimidazolecarboxamide ribotide isomerase) identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00007 InterPro: Histidine biosynthesis protein; High confidence in function and specificity.
  
  
 0.508
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.484
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.