Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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czcBCation efflux system protein; Identified by match to TIGR protein family HMMTIGR01730; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (408 aa)    
Predicted Functional Partners:
czcA
Cation efflux system protein; Identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.984
czcC
Cation efflux system protein; Identified by match to TIGR protein family HMMTIGR01730; Family membership.
  
 
 0.875
macB
ABC transporter, ATP-binding protein/permease, putative; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.845
czcA2
Identified by sequencesimilarity; putative InterPro: Heavy metal efflux pump CzcA; High confidence in function and specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.836
czcA3
(cobalt/zinc/cadmium efflux RND transporterpermease protein CzcA family) identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.831
czcA1
(CzcA) cobalt/zinc/cadmium efflux RND transporterpermease protein (CzcA family) identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.830
czcB3
(heavy metal RND efflux membrane fusion protein,CzcB family) identified by sequence similarity; putative; Family membership.
  
     0.690
AcrB
AcrB/AcrD/AcrFa family protein; Identified by sequence similarity; putative InterPro: Hydrophobe/amphiphile efflux-1 HAE1; Family membership.
 
 
 0.658
ABO_2746
AcrB/AcrD/AcrF family protein; Identified by sequence similarity; putative InterPro: Acriflavin resistance protein The E.coli acrA and acrB genes encode a multi-drug efflux system that isbelieved to protect the bacterium against hydrophobic inhibitors [MEDLINE:94012493]. Members of this family are integral membrane proteins some of which are involved in drug resistance. Proteins which belong to this family (AcrB/AcrD/AcrF family protein) include the P.aeruginosa multidrug resistance protein mexB, A.eutrophus cation efflux system protein czcA, and various R.meliloti nodulation proteins; [...]
 
 
 0.646
czcC2
Heavy metal RND efflux outer membrane protein,CzcC family; Identified by sequencesimilarity; putative; Family membership.
 
 
 0.644
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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