Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
czcCCation efflux system protein; Identified by match to TIGR protein family HMMTIGR01730; Family membership. (413 aa)    
Predicted Functional Partners:
czcB
Cation efflux system protein; Identified by match to TIGR protein family HMMTIGR01730; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.875
czcA
Cation efflux system protein; Identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 0.816
AcrB
AcrB/AcrD/AcrFa family protein; Identified by sequence similarity; putative InterPro: Hydrophobe/amphiphile efflux-1 HAE1; Family membership.
  
 
 0.710
macB
ABC transporter, ATP-binding protein/permease, putative; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.596
czcB2
Heavy metal RND efflux membrane fusion protein CzcB family identified by sequence similarity; putative; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.563
ABO_0267
Multidrug resistance protein; Putative secreted protein; Function unclear.
  
 
 0.560
ABO_2474
Hypothetical protein predicted by Glimmer/Critica.
       0.533
ABO_1849
(HlyD family secretion protein) identified by match to TIGR protein family HMMTIGR01730 InterPro: HlyD family secretion protein Gram-negative bacteria produce a number of proteins which are secreted into the growth medium by a mechanism that does not require a cleaved N-terminal signal sequence. These proteins, while having different functions, require the help of two or more proteins for their secretion across the cell envelope. These secretion proteins include members belonging to the ABC transporter family (see the relevant entry IPR003439) and a protein belonging to a family which [...]
  
 
 0.444
ABO_0017
Secretion protein HlyD family; Family membership.
  
 
 0.423
ABO_1136
(efflux transporter, membrane fusion protein, putative) identified by match to TIGR protein family HMMTIGR01730 InterPro: HlyD family secretion protein; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.423
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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