STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_2527N-terminal fragment of a phosphoenolpyruvate-protein phosphotransferase; identified by sequence similarity to Pfam family protein PF00391, PF01590, PF02896 Interpro: belongs to the pep-utilizing enzymes family: IPR00593, IPR006318/IPR000121; Family membership. (147 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-homocystei ne methyltra; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.900
ABO_1324
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.900
metY
(O-acetylhomoserine sulfhydrylase, O-acetylhomoserine (thiol)-lyase, oah sulfhydrylase, homocysteine synthase) identified by sequence similarity; identified by match to PFAM protein family HMMPF01053; putative InterPro: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; High confidence in function and specificity.
     
  0.900
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.900
ptsO
Phosphotransferase system HPr-related protein NPr identified by sequencesimilarity; putative InterPro: Phosphocarrier HPr protein; Family membership.
  
 
 
 0.822
ABO_1083
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.462
ptsN
Phosphotransferase system, nitrogen regulatory IIA protein; Identified by sequencesimilarity; putative InterPro: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; Family membership.
  
   
 0.426
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Identified by sequence similarity; putative part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein; High confidence in function and specificity.
  
     0.403
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.