STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABO_2571Thiamine biosynthesis protein ThiS; Region start changed from 2912636 to 2912648 (-12 bases). (65 aa)    
Predicted Functional Partners:
thiG
thiG protein, putative; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.997
moeB
Molybdopterin biosynthesis MoeB proteinputative identified by sequencesimilarity; putative InterPro: UBA/THIF-type NAD/FAD binding fold; Family membership.
  
 
 0.913
ABO_2570
Conserved hypothetical protein; Identified by sequencesimilarity; putative.
       0.865
ABO_0609
MutT/nudix family protein/thiamine-phosphatepyrophosphorylase, putative; Identified by sequencesimilarity; putative InterPro: Mutator MutT involved in the go system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from dna and the nucleotide pool. 8-oxo-dgtp is inserted opposite da and dc residues of template dna with almost equal efficiency thus leading to a.t to g.c transversions. mutt specifically degrades 8-oxo-dgtp to the monophosphate belongs to the nudix hydrolase family; High confidence in function and specificity.
 
  
 0.845
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.834
thiC
Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.785
thiD
Adenine phosphoribosyltransferase; (phosphomethylpyrimidine kinase) identified by sequencesimilarity; putative; High confidence in function and specificity.
  
    0.767
ABO_0470
Oxidoreductase FAD-binding identified by sequencesimilarity; putative InterPro: D-amino acid oxidase; Function unclear.
 
  
 0.706
ydaO
Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
  
 
 0.555
mesJ
Cell cycle protein MesJ, putative; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
 0.547
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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