STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_2616Transcriptional regulator ArsR family identified by match to PFAM protein family HMMPF01022 InterPro: SAM (and some other nucleotide) binding motif; Family membership. (324 aa)    
Predicted Functional Partners:
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
    
 0.892
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.736
ABO_1784
Non-ribosomal peptide synthase fragment, contains condensation, fatty-acid-CoA ligase and thioesterase domains. identified by sequence similarity; putative InterPro: AMP-dependent synthetase and ligase; Family membership.
   
 0.700
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
    
  0.601
copA-2
Copper-transporting P-type ATPase (EC 3.6.3.4); High confidence in function and specificity.
  
 
 0.597
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.597
ahcy
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
   
 0.596
ABO_0251
Deacetylase family protein identified by sequence similarity; putative InterPro: Histone deacetylase family; Family membership.
   
 0.595
cheW
(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.
  
   
 0.583
ABO_1244
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF01118.
  
 0.580
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.