Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mvaBhydroxymethylglutaryl-CoA lyase; Identified by sequence similarity; putative InterPro: HMG-CoA Lyase-like family; High confidence in function and specificity; Belongs to the alpha-IPM synthase/homocitrate synthase family. (350 aa)    
Predicted Functional Partners:
ABO_1238
enoyl-CoA hydratase/isomerase, putative; Identified by match to PFAM protein family HMMPF00378, putative InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
 0.995
ech2
(enoyl-CoA hydratase/isomerase FadB1x) identified by sequence similarity; putative InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
 
 0.993
acsA-2
acetoacetyl-CoA synthetase; Identified by sequencesimilarity; putative InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity.
 
 0.943
fadA1
acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.920
fadAx
acetyl-CoA C-acetyltransferase; (3-ketoacyl-CoA thiolase) identified by sequencesimilarity; putative InterPro: Thiolase; Specificity unclear; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.920
fadA
(Acetyl CoA acetyltransferase) identified by sequence similarity; putative InterPro: Thiolase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.920
fadA2
3-oxoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 
 0.920
ABO_1712
acetyl-CoA C-acyltransferase identified by match to PFAM protein family HMMPF00108 InterPro: Thiolase; Function unclear; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.920
fadA3
3-ketoacyl-CoA thiolase; Identified by match to PFAM protein family HMMPF00108 InterPro: thiolase family protein; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.920
sucB
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
 
 0.841
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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