STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkB1Alkane 1-monooxygenase; Catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C5-C12 hydrocarbons. Belongs to the fatty acid desaturase type 1 family. AlkB subfamily. (404 aa)    
Predicted Functional Partners:
alkH
(aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity.
    
 0.960
alkB2
Alkane-1-monooxygenase; Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C8-C16 hydrocarbons; Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
  
  
0.928
alkG
Rubredoxin; Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
 
  
 0.923
adhC
adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
    
 0.901
aldh1
Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.
     
  0.900
alkS
alkB1GHJ regulator; This protein activates the expression of AlkB1 in the presence of alkanes.
 
   
 0.864
ABO_1717
Flavodoxin reductases (ferredoxin-NADPH reductase)putative; (oxidoreductase FAD-binding putative) identified by sequencesimilarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership.
 
  
 0.623
rubA
Rubredoxin; Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
 
  
 0.620
alkJ
Alcohol dehydrogenase; Identified by sequence similarity; putative identified by match to PFAM protein families HMMPF00732 and HMMPF05199; putative InterPro: Glucose-methanol-choline (GMC) oxidoreductase; High confidence in function and specificity.
     
 0.595
ABO_0670
Oxidoreductase (acting on iron-sulfur proteins as donors with NAD+ or NADP+ as acceptor) identified by sequence similarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership.
  
 0.504
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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