| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABO_0509 | aldh1 | ABO_0509 | ABO_0962 | (aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.925 |
| ABO_0509 | alkH | ABO_0509 | ABO_2709 | (aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.925 |
| ABO_0509 | mmsA | ABO_0509 | ABO_0020 | (aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | (methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity. | 0.926 |
| AKR1A1 | adhC | ABO_2414 | ABO_0117 | (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership. | adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.924 |
| AKR1A1 | aldh1 | ABO_2414 | ABO_0962 | (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.922 |
| AKR1A1 | alkH | ABO_2414 | ABO_2709 | (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.910 |
| acsA | aldh1 | ABO_0334 | ABO_0962 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.912 |
| acsA | alkH | ABO_0334 | ABO_2709 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.912 |
| acsA | mmsA | ABO_0334 | ABO_0020 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | (methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity. | 0.912 |
| acsA | mmsB | ABO_0334 | ABO_0022 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; High confidence in function and specificity. | 0.823 |
| acsA | mmsB-2 | ABO_0334 | ABO_1503 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase; Identified by sequencesimilarity; putative; Family membership. | 0.804 |
| adhC | AKR1A1 | ABO_0117 | ABO_2414 | adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership. | 0.924 |
| adhC | aldh1 | ABO_0117 | ABO_0962 | adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.916 |
| adhC | alkB1 | ABO_0117 | ABO_2707 | adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Alkane 1-monooxygenase; Catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C5-C12 hydrocarbons. Belongs to the fatty acid desaturase type 1 family. AlkB subfamily. | 0.903 |
| adhC | alkH | ABO_0117 | ABO_2709 | adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.916 |
| aimE | aldh1 | ABO_1980 | ABO_0962 | Aliphatic amidase; Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.910 |
| aimE | alkH | ABO_1980 | ABO_2709 | Aliphatic amidase; Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.910 |
| aldh1 | ABO_0509 | ABO_0962 | ABO_0509 | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | (aminotransferase, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.925 |
| aldh1 | AKR1A1 | ABO_0962 | ABO_2414 | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership. | 0.922 |
| aldh1 | acsA | ABO_0962 | ABO_0334 | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.912 |