STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureA(urease gamma subunit, urea amidohydrolase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00547 and TIGRFAM protein family HMMTIGR00193 InterPro: Urease gamma subunit; High confidence in function and specificity. (100 aa)    
Predicted Functional Partners:
ureC
(urease alpha subunit, urea amidohydrolase) identified by sequence similarity; putative identified by match to PFAM protein families: HMMPF01979 and HMMPF00449; putative; High confidence in function and specificity; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureB
(urease beta subunit, urea amidohydrolase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00699 and TIGRFAM protein family HMMTIGR00192 InterPro: Urease beta subunit; High confidence in function and specificity.
 0.999
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.979
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 0.978
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.976
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.934
uahA
Urea carboxylase/allophanate hydrolase; Urea carboxylase; urease (ATP-hydrolysing); urea amidolyase/allophanate hydrolase [EC:6.3.4.6 3.5.1.54] identified by sequence similarity; putative InterPro: DUF183; Family membership.
     
  0.900
ABO_2506
(amidase family protein, putative) identified by sequencesimilarity; putative InterPro: Amidase; Family membership.
     
  0.900
ureJ
Urease accessory protein UreJ; Identified by sequence similarity; putative; Family membership.
       0.454
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
    0.420
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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