STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (319 aa)    
Predicted Functional Partners:
SDJ98036.1
Hypothetical protein.
 
    0.961
SDJ97995.1
Ferrous iron transport protein B.
 
     0.899
SDJ97951.1
Ferrous iron transport protein A.
       0.672
SDK08778.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.532
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
   
 0.526
SDK11324.1
CubicO group peptidase, beta-lactamase class C family.
  
   
 0.474
SDK07685.1
Protein of unknown function.
  
     0.457
SDK21756.1
Diacylglycerol kinase.
  
 
  0.440
SDK76008.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
       0.438
SDK84888.1
iron(III) transport system substrate-binding protein.
  
     0.437
Your Current Organism:
Natronincola ferrireducens
NCBI taxonomy Id: 393762
Other names: DSM 18346, N. ferrireducens, Natronincola ferrireducens Zhilina et al. 2009, VKM B-2402, strain Z-0511
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