STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK60368.1PAS domain S-box-containing protein. (494 aa)    
Predicted Functional Partners:
SDK76237.1
Hpt domain-containing protein.
    
 0.940
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.913
SDK83138.1
Signal transduction histidine kinase.
   
 0.902
SDK71443.1
RNA polymerase, sigma 54 subunit, RpoN/SigL.
 
  
 0.849
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.820
SDJ91704.1
HDIG domain-containing protein.
    
 0.785
SDJ99303.1
PAS domain S-box-containing protein.
    
 0.778
SDK76200.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.778
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 0.734
SDK83734.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
   0.709
Your Current Organism:
Natronincola ferrireducens
NCBI taxonomy Id: 393762
Other names: DSM 18346, N. ferrireducens, Natronincola ferrireducens Zhilina et al. 2009, VKM B-2402, strain Z-0511
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