STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabH_23-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)    
Predicted Functional Partners:
fabD
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
fabF
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.994
fabG_2
3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.966
FabG_1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.936
lpxC
hydroxymyristoyl-ACP dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
  
 0.934
PorA_1
Racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.829
HQ45_03640
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.804
HQ45_03645
2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
porB
2-oxoglutarate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
porA_2
2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
Your Current Organism:
Porphyromonas crevioricanis
NCBI taxonomy Id: 393921
Other names: ATCC 55563, CCUG 47702 [[Porphyromonas cansulci]], JCM 13913 [[Porphyromonas cansulci]], JCM 15906, NCTC 12858 [[Porphyromonas cansulci]], NUM 402, P. crevioricanis, Porphyromonas cansulci, VPB 4875 [[Porphyromonas cansulci]]
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