Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACP23919.1Fructokinase protein. (308 aa)    
Predicted Functional Partners:
ACP26226.1
Mannitol dehydrogenase.
 
  
 0.954
aglA1
Alpha-glucosidase.
 
  
 0.948
aglA2
Alpha-glucosidase.
    
 0.940
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
 
  
 0.928
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.921
pgi-2
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.921
pfp
Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.920
glmS2
Isomerizing glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.915
ACP27257.1
Glucosamine--fructose-6-phosphate aminotransferase.
  
 
 0.915
ACP26788.1
Mannose-6-phosphate isomerase.
    
 0.908
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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