Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACP23937.1N-6 DNA methylase. (511 aa)    
Predicted Functional Partners:
ACP23938.1
Putative restriction endonuclease type I, S subunit.
 
 
 0.999
HsdR
Putative restriction endonuclease type I with R subunit / type III with Res subunit.
 
 
 0.989
ACP23939.1
Hypothetical protein.
       0.790
ACP24377.1
Hypothetical protein.
  
  
 0.612
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
    
 
 0.577
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.511
ACP24009.1
Beta-ketoacyl synthase.
 
 
 0.499
ACP25730.1
Probable lipopolysaccharide modification acyltransferase.
   
    0.442
ccrM
Modification methylase SmeIP; Adenine-specificmethyltransferase SmeIP; M.SmeI; M.CcrMI; Belongs to the N(4)/N(6)-methyltransferase family.
     
 0.427
ACP24399.1
long-chain-fatty-acid--CoA ligase.
   
 
 0.423
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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