Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RirAPutative transcriptional regulator, Rrf2 family. (154 aa)    
Predicted Functional Partners:
ACP25308.1
Cysteine desulfurase.
  
  
 0.850
ACP25039.1
Possible nitrogen-fixing NifU-like protein.
  
  
 0.605
ACP24141.1
Extracelluar solute-binding protein, family 1.
  
  
 0.545
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.509
ACP25883.1
Molecular chaperone, DnaJ family.
  
  
 0.463
fixN2
Cytochrome-c oxidase FixN2; Belongs to the heme-copper respiratory oxidase family.
  
  
 0.437
fixN1
Cytochrome-c oxidase, FixN chain; Belongs to the heme-copper respiratory oxidase family.
  
  
 0.437
sufB
Transport protein associated with Fe-S cluster assembly SufB.
     
 0.435
fixG
Nitrogen fixation protein FixG.
  
  
 0.432
dppA
Periplasmic dipeptide ABC transport protein precursor DppA.
     
 0.421
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
Server load: medium (54%) [HD]