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hisZ protein (Sinorhizobium fredii NGR234) - STRING interaction network
"hisZ" - ATP phosphoribosyltransferase regulatory subunit in Sinorhizobium fredii NGR234
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (379 aa)    
Predicted Functional Partners:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily (231 aa)
 
  0.998
hisE
annotation not available (107 aa)
 
   
  0.927
hisS
annotation not available (507 aa)
 
   
0.916
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily (335 aa)
   
 
  0.817
NGR_c04040
annotation not available (235 aa)
              0.675
NGR_c12490
annotation not available (202 aa)
   
          0.583
NGR_c36180
annotation not available (206 aa)
   
          0.539
NGR_c05440
annotation not available (182 aa)
   
          0.536
NGR_c36140
annotation not available (350 aa)
           
  0.532
NGR_c27130
annotation not available (258 aa)
   
          0.517
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium fredii NGR234, Sinorhizobium sp. NGR234
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