Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kefBGlutathione-regulated potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (618 aa)    
Predicted Functional Partners:
ACP27358.1
NAD(P)H dehydrogenase; Quinone.
  
 
 0.909
ACP27359.1
Hypothetical protein associated with NAD(P)H dehydrogenase.
  
 
 0.909
ACP24068.1
Conserved hypothetical protein.
    
   0.751
flgF
Flagellar basal-body rod protein FlgF; Belongs to the flagella basal body rod proteins family.
    
   0.751
flgG
Flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.
    
   0.751
ACP24277.1
Putative flagella associated protein.
    
   0.751
ACP24218.1
Putative Zn-dependent protease, PmbA-like protein.
     
 0.613
nnrD
Putative carbohydrate kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the re [...]
  
  
 0.588
ribA
Riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
 
 0.586
gshB2
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
  
  
 0.582
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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