Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysDSulfate adenylyltransferase, subunit 2. (317 aa)    
Predicted Functional Partners:
cysN
Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 0.999
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
 
 0.996
cysQ
Putative inositol monophosphatase involved in exopolysaccharide production; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
 
 0.971
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
  
 0.923
ACP25088.1
Sulfite reductase [NADPH] hemoprotein beta-component.
 
  
 0.905
cobG
precorrin-3B synthase CobG.
  
  
 0.853
cysK2
Cysteine synthase protein.
  
  
 0.731
cysK1
Cysteine synthase A.
  
  
 0.731
cobA
Porphyrin biosynthesis protein cobA; Belongs to the precorrin methyltransferase family.
 
  
 0.665
ACP25089.1
Putative oxidoreductase.
  
  
 0.544
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
Server load: medium (46%) [HD]