Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
betCCholine-sulfatase. (512 aa)    
Predicted Functional Partners:
betB
Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
   
 0.885
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
  
 0.867
nirV
NirV periplasmic nitrate reductase.
  
   0.808
betI
Putative TetR family transcriptional regulator; Repressor involved in choline regulation of the bet genes.
 
   
 0.729
ACP24009.1
Beta-ketoacyl synthase.
 
 
 0.628
lcdH
Bifunctional 3-hydroxyacyl-CoA dehydrogenase/thioesterase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.
 
     0.548
ACP24399.1
long-chain-fatty-acid--CoA ligase.
  
 
 0.518
ACP26608.1
Hypothetical protein.
   
 0.480
gltB1
Glutamate synthase [NADPH] large chain.
   
  
 0.471
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.453
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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