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glnE protein (Sinorhizobium fredii NGR234) - STRING interaction network
"glnE" - Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme in Sinorhizobium fredii NGR234
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glnEBifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] (985 aa)    
Predicted Functional Partners:
NGR_c15340
annotation not available (158 aa)
            0.813
glnD
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism (965 aa)
   
   
  0.779
NGR_c07850
annotation not available (465 aa)
 
          0.755
NGR_c14750
annotation not available (112 aa)
 
 
  0.743
NGR_c07840
annotation not available (233 aa)
         
  0.717
glnA3
Glutamine synthetase I; glutamate--ammonia ligase I; GSI (469 aa)
 
     
  0.709
NGR_c31500
annotation not available (112 aa)
 
 
  0.688
gltB1
annotation not available (1574 aa)
   
   
  0.558
cycH
annotation not available (381 aa)
 
          0.522
NGR_c31490
Ammonium transporter; Amt family (475 aa)
         
  0.516
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium fredii NGR234, Sinorhizobium sp. NGR234
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