| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fhs | purC | NGR_c23560 | NGR_c16190 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | 0.870 |
| fhs | purD | NGR_c23560 | NGR_c04740 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylamine--glycine ligase; GARS; glycinamideribonucleotide synthetase; phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.692 |
| fhs | purF | NGR_c23560 | NGR_c08750 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.817 |
| fhs | purH | NGR_c23560 | NGR_c33280 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Bifunctional purine biosynthesis protein PurH;includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.988 |
| fhs | purK | NGR_c23560 | NGR_c28310 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.448 |
| fhs | purL | NGR_c23560 | NGR_c16260 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase II (FGAMsynthase II) PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.780 |
| fhs | purM | NGR_c23560 | NGR_c09330 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine cyclo-ligase; AIRS; Phosphoribosyl-aminoimidazole synthetase; AIR synthase. | 0.456 |
| fhs | purN | NGR_c23560 | NGR_c09320 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Putative 5'-phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.980 |
| fhs | purQ | NGR_c23560 | NGR_c16210 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase I (FGAMsynthase I) PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...] | 0.448 |
| fhs | purS | NGR_c23560 | NGR_c16200 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...] | 0.422 |
| purC | fhs | NGR_c16190 | NGR_c23560 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.870 |
| purC | purD | NGR_c16190 | NGR_c04740 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Phosphoribosylamine--glycine ligase; GARS; glycinamideribonucleotide synthetase; phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.993 |
| purC | purF | NGR_c16190 | NGR_c08750 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.978 |
| purC | purH | NGR_c16190 | NGR_c33280 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Bifunctional purine biosynthesis protein PurH;includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.987 |
| purC | purK | NGR_c16190 | NGR_c28310 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.998 |
| purC | purL | NGR_c16190 | NGR_c16260 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Phosphoribosylformylglycinamidine synthase II (FGAMsynthase II) PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.964 |
| purC | purM | NGR_c16190 | NGR_c09330 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Phosphoribosylformylglycinamidine cyclo-ligase; AIRS; Phosphoribosyl-aminoimidazole synthetase; AIR synthase. | 0.995 |
| purC | purN | NGR_c16190 | NGR_c09320 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Putative 5'-phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.982 |
| purC | purQ | NGR_c16190 | NGR_c16210 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Phosphoribosylformylglycinamidine synthase I (FGAMsynthase I) PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...] | 0.978 |
| purC | purS | NGR_c16190 | NGR_c16200 | Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) PurC. | Phosphoribosylformylglycinamidine synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...] | 0.981 |