Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACP24746.1Putative amidase. (442 aa)    
Predicted Functional Partners:
ACP26586.1
Conserved hypothetical protein.
 
     0.727
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.632
glyA
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.560
nrdR
Putative transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.556
ACP24745.1
Putative MarR family transcriptional regulator.
 
   
 0.535
ACP24750.1
Riboflavin synthase alpha chain.
       0.532
nthB
Putative low-molecular weight cobalt-containing nitrile hydratase subunit beta; NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family.
     
  0.500
nthA
Putative high-molecular weight cobalt-containing nitrile hydratase subunit alpha.
     
  0.500
ACP24744.1
Putative transmemrbane protein.
 
   
 0.460
ACP26476.1
Putative periplasmic protein, putative exported protein.
  
   
 0.456
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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