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purL protein (Sinorhizobium fredii NGR234) - STRING interaction network
"purL" - Phosphoribosylformylglycinamidine synthase subunit PurL in Sinorhizobium fredii NGR234
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Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purLPhosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (742 aa)    
Predicted Functional Partners:
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (223 aa)
  0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (221 aa)
 
  0.997
purM
Phosphoribosylformylglycinamidine cyclo-ligase; AIRS; Phosphoribosyl-aminoimidazole synthetase; AIR synthase (356 aa)
 
  0.996
purS
Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (80 aa)
 
 
  0.991
purD
Phosphoribosylamine--glycine ligase; GARS; glycinamideribonucleotide synthetase; phosphoribosylglycinamide synthetase; Belongs to the GARS family (423 aa)
 
  0.980
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (496 aa)
 
 
  0.978
purC
annotation not available (254 aa)
 
 
  0.966
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (520 aa)
 
   
  0.964
purH
annotation not available (536 aa)
 
 
  0.959
carB
Carbamoyl-phosphate synthetase ammonia chain; Belongs to the CarB family (1163 aa)
   
   
  0.943
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium fredii NGR234, Sinorhizobium sp. NGR234
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