Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ACP25837.1HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa)    
Predicted Functional Partners:
ACP25836.1
AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.993
tolC
Putative TolC outer membrane protein.
 
 0.969
ACP25723.1
AcrB/AcrD/AcrF family protein.
 
 0.923
ACP26603.1
Acr/RND family efflux transmembrane transporter.
 
 0.923
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.918
ACP27245.1
Hydrophobe/amphiphile efflux-1 HAE1.
 
 0.917
ACP26248.1
Cation/multidrug efflux pump, RND superfamily; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.913
ACP26247.1
Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.659
mexF
RND multidrug efflux transporter MexF.
 
 
 0.612
ACP23866.1
AcrB/AcrD/AcrF family protein.
 
 
 0.600
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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