Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lldDL-lactate dehydrogenase (cytochrome) protein. (381 aa)    
Predicted Functional Partners:
ACP26379.1
Serine--glyoxylate aminotransferase; SGAT.
  
 0.940
ACP23834.1
NADP-dependent malic enzyme.
    
 0.938
dme
NAD-dependent malic enzyme; NAD-ME.
    
 0.938
ACP25826.1
Putative dehydrogenase/oxidoreductase.
  
 0.934
ACP26581.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.930
ACP27016.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.923
ppdK
Pyruvate, phosphate dikinase (pyruvate, orthophosphatedikinase) PpdK; Belongs to the PEP-utilizing enzyme family.
     
 0.914
pdhA2
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.901
pdhB3
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.900
ACP23999.1
Predicted thiamine pyrophosphate protein, TPP binding domain protein; Belongs to the TPP enzyme family.
  
 
 0.888
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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