Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACP26343.1Putative NADP+ dependent succinate-semialdehyde dehydrogenase. (466 aa)    
Predicted Functional Partners:
sdhB
Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.917
sdhA
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.916
ACP27093.1
Succinic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.912
ACP26872.1
Putative succinate dehydrogenase membrane anchor subunit.
   
 
  0.905
ACP27094.1
HpcH/HpaI aldolase /citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.905
ACP26871.1
Putative succinate dehydrogenase hydrophobic membrane anchor protein.
   
 
 0.903
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.883
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.876
sucA
2-oxoglutarate dehydrogenase, E1 component.
   
 0.876
mdh-2
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.875
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
Server load: medium (48%) [HD]