Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdhmalate/L-sulfolactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (358 aa)    
Predicted Functional Partners:
ACP26203.1
Putative dipeptidase.
  
    0.786
ACP26344.1
Putative hydroxypyruvate isomerase; Belongs to the hyi family.
  
    0.779
ACP26343.1
Putative NADP+ dependent succinate-semialdehyde dehydrogenase.
       0.773
ACP26346.1
Conserved hypothetical protein.
       0.657
ACP26342.1
Putative hydrolase.
 
     0.597
ACP26341.1
Hypothetical protein.
 
     0.596
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.521
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.515
pckA
ATP dependant phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.514
ACP23987.1
Aspartate aminotransferase.
     
 0.508
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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