Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (453 aa)    
Predicted Functional Partners:
ACP26738.1
Maleylacetoacetate isomerase protein.
 
 
 0.997
ACP26744.1
4-hydroxyphenylpyruvate dioxygenase.
 
 0.997
ACP26739.1
Probable aromatic amino acid degradation protein, fumarylacetoacetate hydrolase family.
 
  
 0.961
ACP26742.1
Putative transcriptional regulator, MarR family.
 
     0.889
ACP26740.1
Putative hydrolase.
       0.792
ACP25523.1
Predicted fumarylpyruvate hydrolase protein.
  
  
 0.739
PhhB
Predicted pterin-4-alpha carbinolamine dehydratase.
  
  
 0.657
ACP27368.1
Aspartate aminotransferase.
  
  
 0.460
purU3
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.423
ACP27033.1
enoyl-CoA hydratase/isomerase family protein.
   
  
 0.421
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium sp. NGR234
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