STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (896 aa)
Predicted Functional Partners:
annotation not available (429 aa)
Isocitrate dehydrogenase [NADP]; Oxalosuccinatedecarboxylase; IDH; NADP+-specific ICDH; IDP; Belongs to the isocitrate and isopropylmalate dehydrogenases family (404 aa)
annotation not available (543 aa)
annotation not available (998 aa)
annotation not available (613 aa)
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (321 aa)
annotation not available (896 aa)
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (463 aa)
annotation not available (259 aa)
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 (455 aa)