close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DB31_0621Cell division protein FtsK. (613 aa)    
Predicted Functional Partners:
DB31_1485
Alpha,alpha-trehalose-phosphate synthase.
   
    0.700
DB31_7171
Hypothetical protein.
   
  
 0.584
DB31_2093
Hypothetical protein.
   
    0.576
DB31_4232
Hypothetical protein.
   
    0.576
DB31_0622
Hypothetical protein.
       0.567
DB31_2907
Topoisomerase IV subunit A.
  
    0.553
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.553
DB31_6442
Hypothetical protein.
   
  
 0.523
DB31_2861
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
    0.400
Your Current Organism:
Hyalangium minutum
NCBI taxonomy Id: 394096
Other names: CIP 109157, DSM 14724, H. minutum, Hyalangium minutum Reichenbach 2007, JCM 12630, strain NOCB-2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.