Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DB31_1983Histone acetyltransferase HPA2. (127 aa)    
Predicted Functional Partners:
DB31_1982
D-alanine--D-alanine ligase.
  
  0.941
DB31_5032
Glutamate synthase [NADPH] large chain.
     
  0.899
DB31_1984
Transglutaminase-like superfamily domain protein.
       0.661
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.626
DB31_4931
D-alanine--D-alanine ligase.
  
  0.611
DB31_9061
D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
  
  0.604
DB31_1981
Deoxyguanosinetriphosphate triphosphohydrolase.
     
 0.568
DB31_1980
Hypothetical protein.
       0.564
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.518
DB31_3436
Acetyl-coenzyme A synthetase.
  
 
 0.518
Your Current Organism:
Hyalangium minutum
NCBI taxonomy Id: 394096
Other names: CIP 109157, DSM 14724, H. minutum, Hyalangium minutum Reichenbach 2007, JCM 12630, strain NOCB-2
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.