| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DB31_2308 | DB31_2328 | DB31_2308 | DB31_2328 | O-acetylhomoserine sulfhydrylase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.992 |
| DB31_2308 | DB31_2329 | DB31_2308 | DB31_2329 | O-acetylhomoserine sulfhydrylase. | Hypothetical protein. | 0.837 |
| DB31_2308 | DB31_3012 | DB31_2308 | DB31_3012 | O-acetylhomoserine sulfhydrylase. | Threonine dehydratase. | 0.951 |
| DB31_2308 | DB31_4179 | DB31_2308 | DB31_4179 | O-acetylhomoserine sulfhydrylase. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.883 |
| DB31_2308 | DB31_4824 | DB31_2308 | DB31_4824 | O-acetylhomoserine sulfhydrylase. | Cystathionine beta-synthase. | 0.997 |
| DB31_2308 | DB31_4827 | DB31_2308 | DB31_4827 | O-acetylhomoserine sulfhydrylase. | Cystathionine gamma-lyase. | 0.958 |
| DB31_2308 | ahcY | DB31_2308 | DB31_2378 | O-acetylhomoserine sulfhydrylase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.964 |
| DB31_2308 | ahcY-2 | DB31_2308 | DB31_6908 | O-acetylhomoserine sulfhydrylase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.865 |
| DB31_2308 | metG | DB31_2308 | DB31_1907 | O-acetylhomoserine sulfhydrylase. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.922 |
| DB31_2308 | metK | DB31_2308 | DB31_6907 | O-acetylhomoserine sulfhydrylase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.641 |
| DB31_2328 | DB31_2308 | DB31_2328 | DB31_2308 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase. | 0.992 |
| DB31_2328 | DB31_2329 | DB31_2328 | DB31_2329 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.997 |
| DB31_2328 | DB31_3012 | DB31_2328 | DB31_3012 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Threonine dehydratase. | 0.977 |
| DB31_2328 | DB31_4179 | DB31_2328 | DB31_4179 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.999 |
| DB31_2328 | DB31_4824 | DB31_2328 | DB31_4824 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-synthase. | 0.974 |
| DB31_2328 | DB31_4827 | DB31_2328 | DB31_4827 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-lyase. | 0.992 |
| DB31_2328 | ahcY | DB31_2328 | DB31_2378 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.987 |
| DB31_2328 | ahcY-2 | DB31_2328 | DB31_6908 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.967 |
| DB31_2328 | metG | DB31_2328 | DB31_1907 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.972 |
| DB31_2328 | metK | DB31_2328 | DB31_6907 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.988 |