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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (324 aa)    
Predicted Functional Partners:
DB31_5053
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
    
 0.981
DB31_9095
Homoserine dehydrogenase.
 
  
 0.970
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.955
DB31_2328
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.954
DB31_4824
Cystathionine beta-synthase.
    
  0.952
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.951
DB31_5827
Aminodeoxychorismate lyase.
     
 0.896
ahcY-2
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.620
DB31_1850
Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
  0.593
DB31_5497
Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family.
 
     0.574
Your Current Organism:
Hyalangium minutum
NCBI taxonomy Id: 394096
Other names: CIP 109157, DSM 14724, H. minutum, Hyalangium minutum Reichenbach 2007, JCM 12630, strain NOCB-2
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