Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kuKu domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (318 aa)    
Predicted Functional Partners:
DB31_3548
ATP-dependent DNA ligase.
 
  
 0.960
DB31_2493
ATP-dependent DNA ligase.
 
  
 0.920
DB31_2494
ATP-dependent DNA ligase.
 
  
 0.852
DB31_2133
ATP-dependent DNA ligase.
 
  
 0.744
DB31_5344
DNA topoisomerase IB (poxvirus type).
 
    0.627
DB31_3120
Adenylate cyclase.
       0.601
DB31_3122
Peptidase, M48 family protein.
       0.453
DB31_2134
Helicase domain protein.
  
     0.411
DB31_3119
Hypothetical protein.
       0.406
Your Current Organism:
Hyalangium minutum
NCBI taxonomy Id: 394096
Other names: CIP 109157, DSM 14724, H. minutum, Hyalangium minutum Reichenbach 2007, JCM 12630, strain NOCB-2
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