STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DB31_3484RNA polymerase sigma factor SigZ; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)    
Predicted Functional Partners:
DB31_3483
Lead, cadmium, zinc and mercury transporting ATPase.
       0.709
DB31_3481
Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.603
DB31_3482
Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.603
DB31_3479
Heavy metal RND efflux outer membrane protein, CzcC family protein.
       0.598
DB31_3480
Hypothetical protein.
       0.598
DB31_5739
Putative transmembrane anti-sigma factor.
 
   0.549
DB31_9090
Putative transmembrane anti-sigma factor.
 
   0.516
DB31_4761
Hypothetical protein.
  
 
 0.484
DB31_0049
Flagellar motor switch protein FliM.
   
   0.479
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.476
Your Current Organism:
Hyalangium minutum
NCBI taxonomy Id: 394096
Other names: CIP 109157, DSM 14724, H. minutum, Hyalangium minutum Reichenbach 2007, JCM 12630, strain NOCB-2
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