STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (302 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
ABI67125.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: sil:SPO0361 succinate dehydrogenase, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 0.990
ABI67127.1
KEGG: ccr:CC3527 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 0.988
ABI67098.1
KEGG: ccr:CC0339 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region.
 0.984
ABI67129.1
PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: nha:Nham_3616 succinate dehydrogenase, cytochrome b subunit.
  
 
 0.982
ABI67097.1
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.979
ABI64644.1
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rfr:Rfer_2799 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
  
 
 0.965
ABI65412.1
KEGG: ccr:CC2374 methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
    
 0.958
ABI67128.1
PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: atc:AGR_C_4793 succinate dehydrogenase membrane anchor subunit.
  
 
 0.953
ABI64645.1
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: eba:ebA4589 2-ketoglutarate: NADP oxidoreductase, beta subunit.
  
 
 0.934
Your Current Organism:
Maricaulis maris
NCBI taxonomy Id: 394221
Other names: M. maris MCS10, Maricaulis maris MCS10, Maricaulis maris str. MCS10, Maricaulis maris strain MCS10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.