Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSBOP00000001375Uncharacterized protein. (341 aa)    
Predicted Functional Partners:
IRAK4
Interleukin 1 receptor associated kinase 4.
    
 0.927
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.920
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.893
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.883
RIPK3
Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily.
    
 0.802
TBK1
TANK binding kinase 1.
   
 0.658
IRAK2
Interleukin 1 receptor associated kinase 2.
    
 0.648
PELI3
E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
    
  0.647
ENSSBOP00000005230
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.622
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.592
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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