MAPT protein (Saimiri boliviensis) - STRING interaction network

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Score

MAPT

Microtubule-associated protein. (852 aa)

Predicted Functional Partners:

GSK3B

0.995

TUBA4A

0.989

CASP3

0.987

CAMK2A

0.987

CDK5

0.985

ENSSBOP00000023602

0.982

SNCA

0.981

TUBB6

0.981

ENSSBOP00000001323

0.973

TUBA1B

0.973

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMK2A	MAPT	ENSSBOP00000017998	ENSSBOP00000001595	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	Microtubule-associated protein.	0.987
CASP3	GSK3B	ENSSBOP00000011157	ENSSBOP00000012484	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.426
CASP3	MAPT	ENSSBOP00000011157	ENSSBOP00000001595	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Microtubule-associated protein.	0.987
CASP3	SNCA	ENSSBOP00000011157	ENSSBOP00000007072	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Alpha-synuclein; Belongs to the synuclein family.	0.571
CASP3	TUBB6	ENSSBOP00000011157	ENSSBOP00000011268	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.417
CDK5	GSK3B	ENSSBOP00000003508	ENSSBOP00000012484	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.939
CDK5	MAPT	ENSSBOP00000003508	ENSSBOP00000001595	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Microtubule-associated protein.	0.985
ENSSBOP00000001323	ENSSBOP00000023602	ENSSBOP00000001323	ENSSBOP00000023602	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.994
ENSSBOP00000001323	MAPT	ENSSBOP00000001323	ENSSBOP00000001595	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Microtubule-associated protein.	0.973
ENSSBOP00000001323	TUBA1B	ENSSBOP00000001323	ENSSBOP00000010732	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.966
ENSSBOP00000001323	TUBA4A	ENSSBOP00000001323	ENSSBOP00000026878	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.990
ENSSBOP00000001323	TUBB6	ENSSBOP00000001323	ENSSBOP00000011268	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.911
ENSSBOP00000023602	ENSSBOP00000001323	ENSSBOP00000023602	ENSSBOP00000001323	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.994
ENSSBOP00000023602	MAPT	ENSSBOP00000023602	ENSSBOP00000001595	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Microtubule-associated protein.	0.982
ENSSBOP00000023602	SNCA	ENSSBOP00000023602	ENSSBOP00000007072	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Alpha-synuclein; Belongs to the synuclein family.	0.746
ENSSBOP00000023602	TUBA4A	ENSSBOP00000023602	ENSSBOP00000026878	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.989
ENSSBOP00000023602	TUBB6	ENSSBOP00000023602	ENSSBOP00000011268	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.901
GSK3B	CASP3	ENSSBOP00000012484	ENSSBOP00000011157	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	0.426
GSK3B	CDK5	ENSSBOP00000012484	ENSSBOP00000003508	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.939
GSK3B	MAPT	ENSSBOP00000012484	ENSSBOP00000001595	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Microtubule-associated protein.	0.995