STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UFL1UFM1 specific ligase 1. (792 aa)    
Predicted Functional Partners:
CDK5RAP3
CDK5 regulatory subunit associated protein 3.
   
 
 0.945
DDRGK1
DDRGK domain containing 1.
    
 
 0.942
UBA5
Ubiquitin like modifier activating enzyme 5.
   
 
 0.809
ENSSBOP00000009902
Uncharacterized protein.
    
 
 0.635
ENSSBOP00000015091
Uncharacterized protein.
    
 
 0.635
UFSP2
UFM1 specific peptidase 2.
   
  
 0.625
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 
 0.614
PAWR
Pro-apoptotic WT1 regulator.
      
 0.521
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
      
 0.511
SRD5A3
Steroid 5 alpha-reductase 3.
      
 0.503
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.