node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCKDHA | BCKDHB | ENSSBOP00000001935 | ENSSBOP00000002910 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.999 |
BCKDHA | DHTKD1 | ENSSBOP00000001935 | ENSSBOP00000015340 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Dehydrogenase E1 and transketolase domain containing 1. | 0.786 |
BCKDHA | DLD | ENSSBOP00000001935 | ENSSBOP00000021278 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Dihydrolipoyl dehydrogenase. | 0.996 |
BCKDHA | DLST | ENSSBOP00000001935 | ENSSBOP00000006228 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Dihydrolipoamide S-succinyltransferase. | 0.977 |
BCKDHA | OGDH | ENSSBOP00000001935 | ENSSBOP00000033149 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Oxoglutarate dehydrogenase. | 0.813 |
BCKDHA | OGDHL | ENSSBOP00000001935 | ENSSBOP00000003989 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Oxoglutarate dehydrogenase like. | 0.719 |
BCKDHA | PDHB | ENSSBOP00000001935 | ENSSBOP00000021874 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
BCKDHA | SUCLA2 | ENSSBOP00000001935 | ENSSBOP00000027110 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.493 |
BCKDHA | SUCLG1 | ENSSBOP00000001935 | ENSSBOP00000017219 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.746 |
BCKDHA | SUCLG2 | ENSSBOP00000001935 | ENSSBOP00000017958 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.661 |
BCKDHB | BCKDHA | ENSSBOP00000002910 | ENSSBOP00000001935 | Branched chain keto acid dehydrogenase E1 subunit beta. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
BCKDHB | DHTKD1 | ENSSBOP00000002910 | ENSSBOP00000015340 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dehydrogenase E1 and transketolase domain containing 1. | 0.798 |
BCKDHB | DLD | ENSSBOP00000002910 | ENSSBOP00000021278 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dihydrolipoyl dehydrogenase. | 0.997 |
BCKDHB | DLST | ENSSBOP00000002910 | ENSSBOP00000006228 | Branched chain keto acid dehydrogenase E1 subunit beta. | Dihydrolipoamide S-succinyltransferase. | 0.973 |
BCKDHB | OGDH | ENSSBOP00000002910 | ENSSBOP00000033149 | Branched chain keto acid dehydrogenase E1 subunit beta. | Oxoglutarate dehydrogenase. | 0.823 |
BCKDHB | OGDHL | ENSSBOP00000002910 | ENSSBOP00000003989 | Branched chain keto acid dehydrogenase E1 subunit beta. | Oxoglutarate dehydrogenase like. | 0.735 |
BCKDHB | PDHB | ENSSBOP00000002910 | ENSSBOP00000021874 | Branched chain keto acid dehydrogenase E1 subunit beta. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.709 |
BCKDHB | SUCLA2 | ENSSBOP00000002910 | ENSSBOP00000027110 | Branched chain keto acid dehydrogenase E1 subunit beta. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.456 |
BCKDHB | SUCLG1 | ENSSBOP00000002910 | ENSSBOP00000017219 | Branched chain keto acid dehydrogenase E1 subunit beta. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.783 |
BCKDHB | SUCLG2 | ENSSBOP00000002910 | ENSSBOP00000017958 | Branched chain keto acid dehydrogenase E1 subunit beta. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.637 |