node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NADSYN1 | NMNAT2 | ENSSBOP00000005809 | ENSSBOP00000002692 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide nucleotide adenylyltransferase 2. | 0.980 |
NADSYN1 | NT5E | ENSSBOP00000005809 | ENSSBOP00000023263 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.784 |
NADSYN1 | NUDT12 | ENSSBOP00000005809 | ENSSBOP00000013254 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nudix hydrolase 12. | 0.981 |
NADSYN1 | QPRT | ENSSBOP00000005809 | ENSSBOP00000017489 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.927 |
NADSYN1 | SIRT2 | ENSSBOP00000005809 | ENSSBOP00000004932 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.937 |
NADSYN1 | SIRT3 | ENSSBOP00000005809 | ENSSBOP00000006898 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.937 |
NADSYN1 | SIRT4 | ENSSBOP00000005809 | ENSSBOP00000001563 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.937 |
NMNAT2 | NADSYN1 | ENSSBOP00000002692 | ENSSBOP00000005809 | Nicotinamide nucleotide adenylyltransferase 2. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.980 |
NMNAT2 | NT5C | ENSSBOP00000002692 | ENSSBOP00000036842 | Nicotinamide nucleotide adenylyltransferase 2. | 5', 3'-nucleotidase, cytosolic. | 0.913 |
NMNAT2 | NT5C2 | ENSSBOP00000002692 | ENSSBOP00000007894 | Nicotinamide nucleotide adenylyltransferase 2. | 5'-nucleotidase, cytosolic II. | 0.913 |
NMNAT2 | NT5E | ENSSBOP00000002692 | ENSSBOP00000023263 | Nicotinamide nucleotide adenylyltransferase 2. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.967 |
NMNAT2 | NT5M | ENSSBOP00000002692 | ENSSBOP00000024747 | Nicotinamide nucleotide adenylyltransferase 2. | 5',3'-nucleotidase, mitochondrial. | 0.909 |
NMNAT2 | NUDT12 | ENSSBOP00000002692 | ENSSBOP00000013254 | Nicotinamide nucleotide adenylyltransferase 2. | Nudix hydrolase 12. | 0.913 |
NMNAT2 | QPRT | ENSSBOP00000002692 | ENSSBOP00000017489 | Nicotinamide nucleotide adenylyltransferase 2. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.979 |
NMNAT2 | SIRT2 | ENSSBOP00000002692 | ENSSBOP00000004932 | Nicotinamide nucleotide adenylyltransferase 2. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.916 |
NMNAT2 | SIRT3 | ENSSBOP00000002692 | ENSSBOP00000006898 | Nicotinamide nucleotide adenylyltransferase 2. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.917 |
NMNAT2 | SIRT4 | ENSSBOP00000002692 | ENSSBOP00000001563 | Nicotinamide nucleotide adenylyltransferase 2. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.916 |
NT5C | NMNAT2 | ENSSBOP00000036842 | ENSSBOP00000002692 | 5', 3'-nucleotidase, cytosolic. | Nicotinamide nucleotide adenylyltransferase 2. | 0.913 |
NT5C | NT5C2 | ENSSBOP00000036842 | ENSSBOP00000007894 | 5', 3'-nucleotidase, cytosolic. | 5'-nucleotidase, cytosolic II. | 0.938 |
NT5C | NT5E | ENSSBOP00000036842 | ENSSBOP00000023263 | 5', 3'-nucleotidase, cytosolic. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.935 |