node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F2 | PCSK4 | ENSSBOP00000007711 | ENSSBOP00000015025 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Proprotein convertase subtilisin/kexin type 4. | 0.621 |
F2 | PROC | ENSSBOP00000007711 | ENSSBOP00000032652 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.970 |
FBN1 | PCSK4 | ENSSBOP00000016429 | ENSSBOP00000015025 | Fibrillin 1. | Proprotein convertase subtilisin/kexin type 4. | 0.622 |
FBN1 | TGFB1 | ENSSBOP00000016429 | ENSSBOP00000004252 | Fibrillin 1. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.652 |
MMP11 | PCSK4 | ENSSBOP00000016993 | ENSSBOP00000015025 | Matrix metallopeptidase 11. | Proprotein convertase subtilisin/kexin type 4. | 0.665 |
PCSK4 | F2 | ENSSBOP00000015025 | ENSSBOP00000007711 | Proprotein convertase subtilisin/kexin type 4. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.621 |
PCSK4 | FBN1 | ENSSBOP00000015025 | ENSSBOP00000016429 | Proprotein convertase subtilisin/kexin type 4. | Fibrillin 1. | 0.622 |
PCSK4 | MMP11 | ENSSBOP00000015025 | ENSSBOP00000016993 | Proprotein convertase subtilisin/kexin type 4. | Matrix metallopeptidase 11. | 0.665 |
PCSK4 | PDGFA | ENSSBOP00000015025 | ENSSBOP00000019121 | Proprotein convertase subtilisin/kexin type 4. | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | 0.573 |
PCSK4 | PDGFB | ENSSBOP00000015025 | ENSSBOP00000027945 | Proprotein convertase subtilisin/kexin type 4. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.593 |
PCSK4 | PROC | ENSSBOP00000015025 | ENSSBOP00000032652 | Proprotein convertase subtilisin/kexin type 4. | Uncharacterized protein. | 0.630 |
PCSK4 | PROS1 | ENSSBOP00000015025 | ENSSBOP00000037218 | Proprotein convertase subtilisin/kexin type 4. | Protein S. | 0.582 |
PCSK4 | SCG5 | ENSSBOP00000015025 | ENSSBOP00000038276 | Proprotein convertase subtilisin/kexin type 4. | Secretogranin V. | 0.596 |
PCSK4 | SPACA1 | ENSSBOP00000015025 | ENSSBOP00000031414 | Proprotein convertase subtilisin/kexin type 4. | Sperm acrosome associated 1. | 0.599 |
PCSK4 | TGFB1 | ENSSBOP00000015025 | ENSSBOP00000004252 | Proprotein convertase subtilisin/kexin type 4. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.631 |
PDGFA | PCSK4 | ENSSBOP00000019121 | ENSSBOP00000015025 | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | Proprotein convertase subtilisin/kexin type 4. | 0.573 |
PDGFA | PDGFB | ENSSBOP00000019121 | ENSSBOP00000027945 | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.987 |
PDGFB | PCSK4 | ENSSBOP00000027945 | ENSSBOP00000015025 | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | Proprotein convertase subtilisin/kexin type 4. | 0.593 |
PDGFB | PDGFA | ENSSBOP00000027945 | ENSSBOP00000019121 | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | 0.987 |
PROC | F2 | ENSSBOP00000032652 | ENSSBOP00000007711 | Uncharacterized protein. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.970 |