node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ2 | ENSSBOP00000018079 | ENSSBOP00000017428 | ENSSBOP00000018079 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | WD_REPEATS_REGION domain-containing protein. | 0.591 |
COQ2 | ENSSBOP00000024214 | ENSSBOP00000017428 | ENSSBOP00000024214 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.888 |
COQ2 | ENSSBOP00000028326 | ENSSBOP00000017428 | ENSSBOP00000028326 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein. | 0.533 |
COQ2 | FDFT1 | ENSSBOP00000017428 | ENSSBOP00000019399 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Farnesyl-diphosphate farnesyltransferase 1. | 0.609 |
COQ2 | IDI1 | ENSSBOP00000017428 | ENSSBOP00000010092 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate delta isomerase 1. | 0.888 |
COQ2 | LSS | ENSSBOP00000017428 | ENSSBOP00000027407 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.730 |
COQ2 | MVD | ENSSBOP00000017428 | ENSSBOP00000016291 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.471 |
COQ2 | NDUFAF6 | ENSSBOP00000017428 | ENSSBOP00000011475 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.591 |
ENSSBOP00000018079 | COQ2 | ENSSBOP00000018079 | ENSSBOP00000017428 | WD_REPEATS_REGION domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.591 |
ENSSBOP00000018079 | ENSSBOP00000024214 | ENSSBOP00000018079 | ENSSBOP00000024214 | WD_REPEATS_REGION domain-containing protein. | Nudix hydrolase domain-containing protein. | 0.490 |
ENSSBOP00000018079 | ENSSBOP00000028326 | ENSSBOP00000018079 | ENSSBOP00000028326 | WD_REPEATS_REGION domain-containing protein. | Uncharacterized protein. | 0.505 |
ENSSBOP00000018079 | HMGCS1 | ENSSBOP00000018079 | ENSSBOP00000007782 | WD_REPEATS_REGION domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.585 |
ENSSBOP00000018079 | HMGCS2 | ENSSBOP00000018079 | ENSSBOP00000017113 | WD_REPEATS_REGION domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.585 |
ENSSBOP00000018079 | IDI1 | ENSSBOP00000018079 | ENSSBOP00000010092 | WD_REPEATS_REGION domain-containing protein. | Isopentenyl-diphosphate delta isomerase 1. | 0.490 |
ENSSBOP00000018079 | LSS | ENSSBOP00000018079 | ENSSBOP00000027407 | WD_REPEATS_REGION domain-containing protein. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.554 |
ENSSBOP00000018079 | MVD | ENSSBOP00000018079 | ENSSBOP00000016291 | WD_REPEATS_REGION domain-containing protein. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.474 |
ENSSBOP00000024214 | COQ2 | ENSSBOP00000024214 | ENSSBOP00000017428 | Nudix hydrolase domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.888 |
ENSSBOP00000024214 | ENSSBOP00000018079 | ENSSBOP00000024214 | ENSSBOP00000018079 | Nudix hydrolase domain-containing protein. | WD_REPEATS_REGION domain-containing protein. | 0.490 |
ENSSBOP00000024214 | ENSSBOP00000028326 | ENSSBOP00000024214 | ENSSBOP00000028326 | Nudix hydrolase domain-containing protein. | Uncharacterized protein. | 0.547 |
ENSSBOP00000024214 | FDFT1 | ENSSBOP00000024214 | ENSSBOP00000019399 | Nudix hydrolase domain-containing protein. | Farnesyl-diphosphate farnesyltransferase 1. | 0.691 |