node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP11A1 | CYP2F1 | ENSSBOP00000023629 | ENSSBOP00000031473 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | 0.537 |
CYP11A1 | CYP46A1 | ENSSBOP00000023629 | ENSSBOP00000011092 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.587 |
CYP11A1 | CYP4F11 | ENSSBOP00000023629 | ENSSBOP00000000021 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Uncharacterized protein. | 0.689 |
CYP11A1 | CYP7B1 | ENSSBOP00000023629 | ENSSBOP00000027558 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.954 |
CYP19A1 | CYP2F1 | ENSSBOP00000032238 | ENSSBOP00000031473 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | 0.551 |
CYP19A1 | CYP4F11 | ENSSBOP00000032238 | ENSSBOP00000000021 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.576 |
CYP19A1 | CYP7B1 | ENSSBOP00000032238 | ENSSBOP00000027558 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.613 |
CYP2F1 | CYP11A1 | ENSSBOP00000031473 | ENSSBOP00000023629 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.537 |
CYP2F1 | CYP19A1 | ENSSBOP00000031473 | ENSSBOP00000032238 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.551 |
CYP2F1 | CYP46A1 | ENSSBOP00000031473 | ENSSBOP00000011092 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.542 |
CYP2F1 | CYP4F11 | ENSSBOP00000031473 | ENSSBOP00000000021 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.572 |
CYP2F1 | CYP4F2 | ENSSBOP00000031473 | ENSSBOP00000031037 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 4 subfamily F member 2. | 0.586 |
CYP2F1 | CYP7B1 | ENSSBOP00000031473 | ENSSBOP00000027558 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.582 |
CYP2F1 | ENSSBOP00000029242 | ENSSBOP00000031473 | ENSSBOP00000029242 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.587 |
CYP2F1 | SCGB3A2 | ENSSBOP00000031473 | ENSSBOP00000034128 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Secretoglobin family 3A member 2. | 0.597 |
CYP2F1 | TPPP3 | ENSSBOP00000031473 | ENSSBOP00000021846 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | Tubulin polymerization promoting protein family member 3. | 0.578 |
CYP2F1 | WRN | ENSSBOP00000031473 | ENSSBOP00000021357 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | WRN RecQ like helicase. | 0.553 |
CYP46A1 | CYP11A1 | ENSSBOP00000011092 | ENSSBOP00000023629 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.587 |
CYP46A1 | CYP2F1 | ENSSBOP00000011092 | ENSSBOP00000031473 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. | 0.542 |
CYP46A1 | CYP7B1 | ENSSBOP00000011092 | ENSSBOP00000027558 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.711 |