node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABRAXAS1 | BABAM1 | ENSSBOP00000008303 | ENSSBOP00000030733 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 1. | 0.999 |
ABRAXAS1 | BABAM2 | ENSSBOP00000008303 | ENSSBOP00000032091 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 2. | 0.996 |
ABRAXAS1 | BRCA1 | ENSSBOP00000008303 | ENSSBOP00000022189 | Abraxas 1, BRCA1 A complex subunit. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.998 |
ABRAXAS1 | BRCC3 | ENSSBOP00000008303 | ENSSBOP00000039488 | Abraxas 1, BRCA1 A complex subunit. | BRCA1/BRCA2-containing complex subunit 3. | 0.996 |
ABRAXAS1 | ENSSBOP00000026465 | ENSSBOP00000008303 | ENSSBOP00000026465 | Abraxas 1, BRCA1 A complex subunit. | Uncharacterized protein. | 0.912 |
ABRAXAS1 | ENSSBOP00000033659 | ENSSBOP00000008303 | ENSSBOP00000033659 | Abraxas 1, BRCA1 A complex subunit. | Uncharacterized protein. | 0.912 |
ABRAXAS1 | ENSSBOP00000040383 | ENSSBOP00000008303 | ENSSBOP00000040383 | Abraxas 1, BRCA1 A complex subunit. | DUF1725 domain-containing protein. | 0.912 |
ABRAXAS1 | UIMC1 | ENSSBOP00000008303 | ENSSBOP00000038532 | Abraxas 1, BRCA1 A complex subunit. | Ubiquitin interaction motif containing 1. | 0.996 |
ABRAXAS2 | BABAM1 | ENSSBOP00000036772 | ENSSBOP00000030733 | Abraxas 2, BRISC complex subunit. | BRISC and BRCA1 A complex member 1. | 0.990 |
ABRAXAS2 | BABAM2 | ENSSBOP00000036772 | ENSSBOP00000032091 | Abraxas 2, BRISC complex subunit. | BRISC and BRCA1 A complex member 2. | 0.993 |
ABRAXAS2 | BRCA1 | ENSSBOP00000036772 | ENSSBOP00000022189 | Abraxas 2, BRISC complex subunit. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.465 |
ABRAXAS2 | BRCC3 | ENSSBOP00000036772 | ENSSBOP00000039488 | Abraxas 2, BRISC complex subunit. | BRCA1/BRCA2-containing complex subunit 3. | 0.995 |
ABRAXAS2 | SHMT2 | ENSSBOP00000036772 | ENSSBOP00000024801 | Abraxas 2, BRISC complex subunit. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.943 |
ABRAXAS2 | UIMC1 | ENSSBOP00000036772 | ENSSBOP00000038532 | Abraxas 2, BRISC complex subunit. | Ubiquitin interaction motif containing 1. | 0.519 |
BABAM1 | ABRAXAS1 | ENSSBOP00000030733 | ENSSBOP00000008303 | BRISC and BRCA1 A complex member 1. | Abraxas 1, BRCA1 A complex subunit. | 0.999 |
BABAM1 | ABRAXAS2 | ENSSBOP00000030733 | ENSSBOP00000036772 | BRISC and BRCA1 A complex member 1. | Abraxas 2, BRISC complex subunit. | 0.990 |
BABAM1 | BABAM2 | ENSSBOP00000030733 | ENSSBOP00000032091 | BRISC and BRCA1 A complex member 1. | BRISC and BRCA1 A complex member 2. | 0.999 |
BABAM1 | BRCA1 | ENSSBOP00000030733 | ENSSBOP00000022189 | BRISC and BRCA1 A complex member 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.989 |
BABAM1 | BRCC3 | ENSSBOP00000030733 | ENSSBOP00000039488 | BRISC and BRCA1 A complex member 1. | BRCA1/BRCA2-containing complex subunit 3. | 0.996 |
BABAM1 | ENSSBOP00000026465 | ENSSBOP00000030733 | ENSSBOP00000026465 | BRISC and BRCA1 A complex member 1. | Uncharacterized protein. | 0.915 |